Latest News

A protein-blocking injection triggered cartilage regeneration in old mice, raising hopes for a future alternative to knee replacement surgery. The treatment targets 15-PGDH, a protein that rises with age and contributes to tissue decline. Researchers call such age-linked enzymes “gerozymes”, master regulators of ageing. Blocking 15-PGDH thickened knee cartilage across the joint surface in older [...]

Canadian life insurer and asset manager Manulife has boosted its presence in the healthy ageing sector with the launch of a CA$350m Longevity Institute. Valued at US$60bn, Manulife has been active in the longevity space for some time and says the new institute will see it fund ‘innovative research, and key industry collaborations’. Manulife’s chief [...]

Developed with input from over 13,000 participants a new, AI-powered, speech and language software has the potential to speed-up dementia diagnoses, whilst reducing the cost. Memory Tell stems from the work of neuroscientist Adolfo Garcia, Co-founder of the Global Brain Health Institute (GBHI), who, for the last 15 years, has been investigating dementia, digital-biomarkers. In [...]

Microdoses of weight loss drugs like Ozempic could slow ageing and increase longevity, according to new research in mice. The study found that exenatide, a drug with similar chemical make-up to Ozempic, produced molecular changes in mice that opposed typical patterns seen with ageing across multiple organs. Scientists treated mice starting at 11 months of [...]

Cheese eaten at least weekly was linked with a lower dementia risk in a study of nearly 8,000 older adults. Tracking 7,914 people aged 65 or over for three years, the study found a dementia rate of 3.4 per cent among weekly cheese eaters, compared with 4.5 per cent in those who avoided cheese. That [...]

Metformin, a cheap century-old drug, cut insulin use by 12 per cent in adults with type 1 diabetes, a recent Australian study has found. A randomised trial in 40 adults with long-term type 1 diabetes found insulin doses were 12 per cent lower with metformin over six months, with no change in blood sugar control. [...]

Root canal treatment reduces inflammation linked to heart disease and improves blood sugar and cholesterol, suggesting lower diabetes risk, research shows. A study tracking blood chemistry changes in 65 patients following treatment for apical periodontitis (a common infection at the tooth root tip) found significant improvements in metabolic health markers. Successful treatment was linked to [...]

UK deaths from Alzheimer's disease and other dementias hit their highest level since records began, with 6,612 fatalities last year, new research has revealed. The death rate has more than doubled over the past two decades, making dementia one of Scotland's leading causes of death, responsible for one in ten fatalities. Nearly two-thirds of those [...]

Storii has won a US$1.7m Phase II grant to test its telephone reminiscence service in rural older adults, aiming to cut social isolation and improve mental health. The study will run as a clinical trial to assess whether weekly automated calls that prompt life-story questions can boost mood and strengthen carer connections. Reminiscence means guided [...]

Ultra-processed foods harm every major organ system and threaten global health, the world's largest review has revealed. Evidence reviewed by 43 of the world's leading experts reveals that diets high in UPF are associated with overeating, poor nutritional quality and higher exposure to harmful chemicals and additives. A systematic review of 104 long-term studies found [...]