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Researchers say a molecule from gut bacteria may counter insulin resistance in type 2 diabetes. The study reports that trimethylamine (TMA), made by gut microbes from dietary choline, can block a key immune pathway and improve blood sugar control. Scientists found that TMA acts as a natural inhibitor of IRAK4, a protein that drives inflammation [...]
A diabetes and weight loss drug has been shown to cut brain shrinkage in Alzheimer’s by almost 50 per cent. The drug, liraglutide, is a GLP-1 receptor agonist, a class that copies a gut hormone which helps regulate blood sugar and appetite. The family includes semaglutide, known as Wegovy or Ozempic. In a study involving [...]
GPs are failing to support older people with frailty, with only one in six assessed for the condition in 2024/25. Frailty is a syndrome related to ageing in which body systems lose in-built reserves, causing symptoms such as exhaustion and making people more likely to be housebound. Of the 226,000 patients diagnosed with frailty in [...]
A treatment using particles from stem cells can slow and even reverse aspects of age-related memory decline, new research suggests. The study found that tiny vesicles, small sacs released by bone marrow stem cells, helped maintain memory and improved communication between brain areas over two years in an experimental model. Researchers at Boston University worked [...]
High-quality marriages may help protect against obesity by shaping communication between the brain and gut, new research suggests. The study is described as the first to show how social bonds influence weight and eating behaviours through an integrated pathway involving brain activity, metabolism and oxytocin, sometimes called “the love hormone”. The findings suggest relationship quality [...]
Fewer than one in 10 people who could benefit from GLP-1 drug treatment can access it, the WHO warns in its first guidance on obesity medicines. With more than one billion people now obese and projections suggesting this could exceed two billion by 2030, the UN health agency is calling for wider and fairer access [...]
Obesity may speed up Alzheimer's progression, with blood tests detecting early effects more sensitively than PET brain scans, new research suggests. The analysis tracked 407 people over five years, using blood samples and PET scans to spot signs of the disease. PET (positron emission tomography) measures amyloid plaques, sticky protein clumps in the brain, while [...]
Morphocell Technologies has completed a US$50m Series A, after a US$10m add-on, to advance its liver cell therapy towards clinical proof-of-concept. The Montreal firm’s lead programme, ReLiver, aims to provide tissue-engineered replacements for failing livers. It uses induced pluripotent stem cells (iPSCs), adult cells reprogrammed to act like embryonic stem cells, then matured into liver [...]
Agetech World explores the latest business developments in the world of ageing and longevity. US$4.5m NIH Funding for senior care technology Immersive technology company Rendever has secured nearly US$4.5m in grant funding from the National Institutes of Health (NIH) to improve the ageing process through technology-enabled social networks. The funding includes US$3.8m for the Thrive [...]
Dementia has overtaken cancer as the disease Britons fear most, with one in three adults naming it their greatest health concern, new research finds. The findings come from the New Ageing Index, described as the first project to track how the UK thinks and feels about ageing and care over an extended period. Fear of [...]
















