Research

  • The brain ages at different paces according to social and physical environments

    New research has show that countries with greater inequalities – whether economic, pollution or disease-based – exhibited older brain ages. The pace at which the brain ages can vary significantly among individuals, leading to a gap between the estimated biological age of the brain and the chronological age. This difference may be affected by several [...]

  • More people in UK at risk of hereditary heart disease than thought

    More people in the UK are at risk of a hereditary form of cardiac amyloidosis, a potentially fatal heart condition, than previously thought, according to a new study. The study used data from the UK Biobank to analyse the genes of 469,789 people in the UK and found that one in 1,000 possessed genetic variants [...]

  • Researchers develop injectable heart stimulator for emergency situations

    By injecting a solution of nanoparticles around the heart, a new temporary heart stimulator is able to self-assemble, correcting heart arrhythmia in emergency situations with the help of an external power source. After treatment, the electrode spontaneously disappears from the body. Arrhythmia occurs when there are disturbances in the heart’s electrical signals, causing it to [...]

  • Improving dementia diagnosis with AI software

    Researchers have developed a new algorithm capable of pinpointing causes of cognitive decline, using only patient information collected by physicians that can help make dementia diagnosis easier and faster. Although Alzheimer’s is the most common cause of dementia—a catchall term for cognitive deficits that impact daily living, like the loss of memory or language—it’s not [...]

  • Alzheimer’s drug may slow down cognitive decline in Lewy body dementia

    In a new study, cholinesterase inhibitor treatments (ChEIs) have been shown to slow down cognitive decline in Lewy body dementia over five years compared to memantine or no treatment, and were associated with a reduced risk of death in the first year after diagnosis. Dementia with Lewy bodies is a type of dementia that is [...]

  • Multiple sclerosis appears to protect against Alzheimer’s disease

    People with multiple sclerosis (MS) are far less likely than those without the condition to have the molecular hallmarks of Alzheimer’s disease, according to new research. The discovery suggests a new avenue of research through which to seek Alzheimer’s treatments, said Matthew Brier, MD PhD, an assistant professor of neurology and of radiology and the [...]

  • Study uncovers connections between retroelements and ageing

    A new study has suggested novel and surprising insights on the connection between retroelements and the ageing process. Embedded in our DNA, retroelements are remnants of ancient viral infections that are silenced by DNA methylation, an epigenetic mechanism that cells can use to control gene expression. Researchers have shown that analysis of retroelement-based epigenetic signatures [...]

  • Black Americans at greater Alzheimer’s risk

    A new study examining older Black Americans’ perceptions of Alzheimer’s disease has found a lack of awareness of the devastating condition and has proposed strategies for supporting brain health in this population. Absence of awareness of Alzheimer's disease may undermine Black Americans’ ability to identify potential risk of the disease and its impact on their [...]

  • Untreated high blood pressure may increase risk of Alzheimer’s

    New research has revealed that people aged 60 and older with untreated high blood pressure may have an increased risk of Alzheimer’s disease. This is compared to both people who have been or are being treated for high blood pressure as well as people without the chronic condition. Author Matthew J. Lennon, MD, PhD, of [...]

  • Age-related changes spike in our 40s and 60s, shows new study

    A new study has revealed huge biomolecular shifts that contribute to age-related changes in our 40s and 60s. Rather than changing in a gradual manner, researchers have discovered that molecules and microorganisms contained in our body undergo two periods of rapid change at around age 44 and age 60. For the study, researchers analysed the [...]