Research
A highly promising gene therapy has been developed to treat glaucoma – a debilitating eye condition that can lead to complete vision loss, and which affects around 80 million people worldwide. The team from Trinity College Dublin previously showed their therapy offered promise in treating dry age-related macular degeneration (AMD). The work shows how the [...]
New research shows that the Covid-19 lockdowns unusually accelerated brain maturation in adolescents, which was more pronounced in girls. During the Covid-19 lockdowns, governments around the world implemented restrictive measures — such as stay-at-home orders and school closures — to mitigate the spread of the respiratory illness. It’s been well-documented that this disruption of daily [...]
Researchers have uncovered a key reason why a typically normal protein - NSD2 - goes awry and fuels prostate cancer. They found the protein NSD2 alters the function of the androgen receptor, an important regulator of normal prostate development. When androgen receptor binds with NSD2, it causes rapid cell division and growth leading to prostate [...]
Older people are just as capable as younger individuals of remembering musical pieces—but certain parts of their brains must work harder. The study is remarkable because it combines classical music and neurophysiology to map the changes that occur in the brain with age. At Aarhus University Hospital, 76 participants underwent brain scans while listening to [...]
New research has discovered a unique and promising avenue for diagnosing Alzheimer’s disease earlier – by analysing AD biomarkers in blood – so that the impacts of dementia can be reduced. Alzheimer’s is the most common form of dementia, estimated to contribute to 60 to 70 per cent of cases, or more than 33 million cases [...]
Researchers have used fruit flies to uncover a cellular process that cells use to tune how much protein they make through the process of translating RNA into protein. The process is common to many organisms and could dramatically impact the understanding of cancer and longevity. The researchers used Drosophila, a popular choice among researchers because [...]
The UK's Alzheimer’s Society will be investing £9 million to fund three new Doctoral Training Centres designed to support and nurture dementia researchers at the start of their career. Currently only one in five dementia PhD students go on to stay in dementia research often due to underfunding and the challenging nature of academic careers. [...]
A new study has suggested an association between eating eggs and a reduced risk of Alzheimer's dementia in older adults. These findings are important as the prevalence of Alzheimer's dementia — the most common type of dementia—is expected to increase with an aging population. Researchers continue to explore how diet could impact risk for Alzheimer's [...]
Researchers have used real-world data to attempt to emulate a randomised controlled trial testing the effectiveness of two blood thinners, apixaban and warfarin, to prevent stroke in patients with non-valvular atrial fibrillation. The study provides a method to explore the effects of treatments in patients who are underrepresented or excluded from clinical trials. Patients experiencing [...]
Patients with stable coronary artery disease who quit smoking at any timepoint after their diagnosis reduced their risk of a heart attack by almost 50%, according to new research. In contrast, there was minimal impact on cardiovascular risk in patients who reduced their smoking habits. For the study, te international CLARIFY registry (prospeCtive observational LongitudinAl [...]
