Research
The largest genome-wide association study (GWAS) ever performed on osteoarthritis has uncovered over 900 genetic associations. More than 500 of these associations had never been reported before, providing fresh insights into the genetic landscape of the disease. By integrating diverse biomedical datasets, the researchers identified 700 genes with high confidence as being involved in osteoarthritis. [...]
Hydromethylthionine mesylate (HMTM) could potentially be the first oral treatment for Alzheimer’s disease (AD) that targets the tau protein pathology – if it is approved by regulators. The research compared results from HMTM’s recent Phase 3 trial with placebo data from closely matched subjects available from the Critical Path in AD (CPAD) Institute database, which [...]
Some older adults – including those with very low incomes – find themselves getting billed for using digital patient portals to send messages to their doctors and other healthcare providers. A new study suggests that people in their 50s and older have embraced the ability to send and receive secure medical messages with their doctors [...]
A new study has found that osteocytes - a type of bone cell - undergo dramatic structural and functional changes with age that impair their ability to keep our bones strong, offering new insights that could pave the way for better treatments for osteoporosis and age-related bone loss. Ageing and stress can induce cellular senescence [...]
New research indicates that N-acetylcysteine (NAC) - a medicine widely used to treat paracetamol overdose and dietary supplement with anti-inflammatory and antioxidant properties - holds promise in treating hereditary cystatin C amyloid angiopathy (HCCAA) - a rare form of familial dementia found mostly in Icelandic people. Icelandic drug discovery and development company Arctic Therapeutics (ATx) has [...]
Gastrointestinal molecular diagnostics company, Cyted Health, has enrolled the first patient in its 'DETECT-ME' clinical validation study. The study will evaluate the company's advanced molecular assays using esophageal cells to detect Barrett’s Esophagus (BE) and esophageal adenocarcinoma (EAC). EAC is a significant public health concern due to its rising incidence, late-stage diagnosis, and high mortality. [...]
Researchers have demonstrated that by using AI to analyse standard 12-lead electrocardiograph (ECG) data taken from almost half a million people, they were able to create an algorithm to predict the biological age of the heart. This algorithm could be used to identify those most at risk of cardiovascular events and mortality. While everybody’s heart [...]
Some individuals who have had anterior-cruciate-ligament reconstruction (ACLR), the kind of surgery often performed on athletes’ knees, may develop early-onset knee osteoarthritis, a new study has revealed. The study indicates that altered knee joint movement after ACLR could be a contributing factor. The study used a unique dynamic X-ray imaging system to accurately measure knee [...]
Sirio Pharma has announced the launch of a new anti-ageing institute that will work to accelerate research on longevity. The company announced the launch of the Sirio Institute for Anti-Ageing (SIA) at the 2025 Boao Health Food Science Conference & Expo. According to Sirio, the Institute will aim to address population ageing guided by the [...]
People in good socioeconomic conditions, such as high incomes or education levels, face a reduced risk of age-related diseases and show fewer signs of biological ageing than peers of the same age, a new study shows. Social inequalities appear to have a direct impact on the biological ageing process. In a new study, scientists found [...]
