Research
By incorporating hormone (steroid) metabolism pathways into an AI-driven model, they have developed a new system to estimate a person’s biological age a measure of how well their body has aged, rather than just counting the years since birth. We all know someone who seems to defy ageing, people who look younger than their peers [...]
Scientists have shown that the mitochondria powering our cells also control the ability of a DNA repair protein to suppress SASP, which may reduce or delay "inflammaging". In humans and other multicellular organisms, cells multiply. This defining feature allows embryos to grow into adulthood, and enables the healing of the many bumps, bruises and scrapes [...]
In one of the first studies of its kind, researchers have found that proteins and pathways involved in inflammation are associated with changes in bone mineral density (BMD) over time. The research could potentially lead to the identification of biomarkers that would serve as early indicators of a person’s risk for bone health issues later [...]
Mental health disorders in people with chronic obstructive pulmonary disease (COPD) are underdiagnosed and undertreated, leading to worsened symptoms and decreased quality of life, according to a new study. COPD is an inflammatory lung disease, comprising several conditions, including chronic bronchitis and emphysema, and can be caused by genetics and irritants like smoke or pollution. [...]
Resistance or muscle strengthening exercise, using weights or the body itself, may be the best type of exercise for tackling insomnia in older age, suggests a pooled data analysis of the available research. Aerobic exercise or a mix of strength, aerobic, balance, and flexibility exercises also seem to be effective, the analysis indicates. Sleep quality [...]
Researchers have made discoveries about brown fat that may open a new path to helping people stay physically fit as they age. The researchers found that mice lacking a specific gene developed an unusually potent form of brown fat tissue that expanded lifespan and increased exercise capacity by roughly 30 per cent. Now, the team [...]
A set of genes that remain unchanged throughout the ageing process have been identified - a discover that could improve the accuracy of ageing research and provide insights into why some genes stay unchanged while others decline. The study looked at gene activity in 17 different tissues in mice, from one month old to over [...]
A new study has shown that a range of environmental factors, including lifestyle such as smoking and physical activity, and living conditions, have a greater impact on health and premature death than our genes. For the study, researchers used data from nearly half a million UK Biobank participants to assess the influence of 164 environmental [...]
The rise in human life expectancy has slowed down across Europe since 2011, according to research from the University of East Anglia and partners. A new study reveals that the food we eat, physical inactivity and obesity are largely to blame, as well as the Covid pandemic. Of all the countries studied, England experienced the [...]
Research has demonstrated that severe early-life adversity is linked to measurable markers of accelerated brain ageing and can amplify neurodegenerative processes later in life. Stressful or traumatic experiences in childhood have been shown to negatively impact an individual’s health as an adult. Those affected face an increased risk of illness and often suffer from depression, [...]
