Research
A research team has conducted a clinical trial to determine whether low-dose, intermittent rapamycin could safely improve healthspan in older adults. The findings suggest rapamycin may offer measurable benefits for physical function and overall well being, reinforcing its potential as a safe intervention to support healthy ageing. Ageing remains the leading cause of chronic conditions [...]
This month, researchers participating in the Cilento Initiative on Aging Outcomes or CIAO study will gather in Acciaroli (Pollica-Cilento) Salerno, Italy to review a decade of work and plan their next steps. Launched in 2016, the CIAO study seeks to identify key factors (biological, psychological and social) that promote healthy aging and extreme longevity. The [...]
New research has found that fisetin - a natural substance found in fruits and vegetables - helps protect blood vessels from hardening, which is a common problem in older adults and people with kidney disease. This discovery highlights fisetin’s potential to prevent vascular calcification and reduce cardiovascular damage caused by ageing and chronic kidney disease. [...]
Groundbreaking research has revealed how MRI scans can determine the functional age of a person's heart, showing dramatic acceleration in those with unhealthy lifestyles. The revolutionary technique could transform heart disease diagnosis by identifying problems before symptoms appear, potentially saving millions of lives. Scientists at the University of East Anglia (UEA) developed the new approach, [...]
Nearly two-thirds of Americans over 50 wrongly believe Medicare would cover nursing home costs, new polling data reveals. The survey exposes widespread misconceptions about long-term care funding and preparation, with many holding mistaken beliefs about payment options and future needs. University of Michigan researchers found that 62 per cent of older adults incorrectly assume Medicare [...]
Researchers have uncovered crucial evidence that substance use disorders (SUDs) accelerate biological ageing in the brain through distinct molecular mechanisms. The groundbreaking study examines how different substances, such as alcohol, opioids, and stimulants, affect the brain's ageing process at the molecular level, potentially explaining why individuals with SUDs often experience early-onset age-related diseases. The research [...]
A common diabetes drug can reduce the pain of people with knee osteoarthritis and overweight or obesity, possibly delaying the need for knee replacements, new research has found. Metformin, which is commonly prescribed to treat type 2 diabetes, reduced knee arthritis pain over six months in a clinical trial. The randomised clinical trial looked at [...]
Researchers have discovered that expansion of mutant blood cells, a phenomenon linked to ageing, can be found in cancerous tumours, and this is associated with worse outcomes for patients. Understanding the biological interface of age-related genetic changes and diseases of ageing, such as cancer and cardiovascular disease, is important to develop preventative therapies for a [...]
Researchers have found that both low and moderate-high intensity exercise could be valuable tools in the fight against Alzheimer’s. The new research describes the results of the EXERT study (Exercise in Adults with Mild Memory Problems), a multi-site clinical trial of lower or moderate-high intensity exercise in sedentary older adults with amnestic mild cognitive impairment, [...]
New research has revealed that a patient’s muscle quality before total hip arthroplasty may predict their risk of such suboptimal recovery after surgery. Hip replacement surgery, or total hip arthroplasty (THA), can lessen pain and improve function in individuals with hip osteoarthritis, but some patients continue to experience long-term physical deficits - including muscle weakness, [...]
