Research

  • Use of metformin associated with exceptional longevity among older women

    There is increasing interest in finding drugs, known as gerotherapeutics, that can slow ageing and help people live longer. Now, metformin, a common diabetes drug, is being studied because it affects several ageing-related processes. In a multi-institutional study, researchers examined the relationship between metformin use and a longer lifespan among postmenopausal women with type 2 [...]

  • How can we reduce wait times for hip and knee replacement surgeries?

    A co-ordinated referral and team-based care models show promise for reducing waiting times for vital hip and knee replacement surgeries, according to new research. In Canada, there are long wait times for scheduled surgeries, such as hip and knee joint replacements, which can lead to worsening pain and mobility problems and affect overall health. Canada [...]

  • Ageing reduces CAR-T cell effectiveness by impairing metabolism

    As people age, their immune systems become less efficient, posing a challenge for cancer therapies that rely on harnessing immune cells. In a new study published in Nature Cancer, researchers from the University of Lausanne (UNIL), the Lausanne University Hospital (CHUV), the Geneva University Hospitals (HUG) and the Ecole Polytechnique Fédérale de Lausanne (EPFL), show [...]

  • Changes in the ageing heart may lessen the risk of irregular heartbeats

    A team of researchers have discovered that microscopic structural changes in the ageing heart may reduce the risk of irregular heartbeats. Medically known as arrhythmias, irregular heartbeats become more common with age and can lead to health problems. But a new study, carried out by Virginia Tech researchers at the Fralin Biomedical Research Institute at VTC, revealed [...]

  • AI can tackle ageing’s true complexity

    A new study has demonstrated that artificial intelligence can be used not just to accelerate drug discovery, but to fundamentally transform how it’s done - by targeting the full complexity of biological ageing. In a collaboration between Scripps Research and Gero, a biotechnology company focused on ageing, scientists developed a machine learning model trained to [...]

  • Eldercare robot helps people sit and stand, and catches them if they fall

    To help address the eldercare challenge, a team of MIT engineers is looking to robotics. They have built and tested the Elderly Bodily Assistance Robot, or E-BAR, a mobile robot designed to physically support the elderly and prevent them from falling as they move around their homes. The United States population is older than it [...]

  • People with critical cardiovascular disease may benefit from palliative care

    Palliative care may help relieve symptoms and improve quality of life for people with cardiovascular disease and ensure that treatment is aligned with the patient’s personal beliefs and values throughout all stages of illness, according to a new American Heart Association scientific statement. This applies whether they are hospitalised in a cardiac intensive care unit or receiving [...]

  • Current tests are not catching cancer recurrence early enough, say oncologists

    In a new report, oncologists reveal they are seeing more and more patients with advanced cancers, and worry that current tests may not catch cancer recurrence early enough. Based on a survey conducted by The Harris Poll on behalf of Quest Diagnostics, the new report highlights perspectives of medical and surgical oncologists about the prevalence [...]

  • Cell death discovery could lead to next-gen drugs for neurodegenerative conditions

    Researchers have discovered how to block cells dying, in a finding that could lead to new treatments for neurodegenerative conditions like Parkinson’s and Alzheimer’s. The team have identified a small molecule that can selectively block cell death. The findings lay the groundwork for next-generation neuroprotective drugs for degenerative conditions, which currently have no cure or [...]

  • Hearing loss in middle age may accelerate cognitive decline

    A new study has revealed that hearing loss in middle age may accelerate cognitive decline - pointing to the need for greater attention to hearing health as a way to prevent dementia. A study conducted in Brazil on 805 people in their 50s confirmed that those with hearing loss had an increased risk of cognitive [...]