News
NHS England fast-tracks new life-extending blood cancer treatment

NHS patients with an aggressive form of blood cancer are to benefit from a life-extending daily tablet after the health service became Europe’s first to routinely commission the treatment.
The new targeted treatment, quizartinib, can now be prescribed to newly-diagnosed patients with a specific type of leukaemia, boosting their chance of remission and long-term survival.
The treatment will be routinely commissioned and immediately available thanks to NHS England’s Cancer Drugs Fund, which fast-tracks new innovative cancer treatments into standard care.
Professor Peter Johnson, NHS National Clinical Director for Cancer, said: “It’s very good news that patients with this type of leukaemia now have an option that helps their chemotherapy to work better, boosting their chance of remission and long-term survival and offering them precious extra time with their families and friends.
“People who have acute myeloid leukaemia and the specific FLT-3 ITD abnormality will be able to take this oral treatment, quizartinib, which the NHS has fast-tracked.
“The NHS in England has enviable track record of making innovative treatments available and this is the latest in a long list of new cancer drugs to help people to live with and beyond cancer, making life-changing differences to people affected by cancer and their families across the country”.
Acute myeloid leukaemia (AML) aggressively interferes with blood production, leaving the body open to often fatal infections but, with effective treatment, patients can go into remission and in some cases be cured.
Around 3,100 people are diagnosed with this type of cancer in the UK annually, with just over a quarter (27%) of those having the FLT3-ITD genetic mutation and therefore able to receive the new treatment.
The once-a-day tablet will be offered to adults as part of initial treatment alongside chemotherapy, and then for a further 3 years as a maintenance treatment to reduce the likelihood of cancer relapses.
If a patient’s condition has improved enough because of quizartinib and chemotherapy, eligible patients can then be offered stem cell transplants, which can increase the chance of being cured.
For patients not deemed suitable for stem cell transplants, the drug can still be life-extending, enabling them to have more time with their families and loved ones.
The UK’s medicines regulator, the Medicines and Healthcare products Regulatory Agency, determined the safety and effectiveness of the drug earlier this year, noting that patients receiving quizartinib had a median overall survival of 31.9 months compared to 15.1 months for those receiving the placebo. The median survival rate marks the point at which half of patients had survived in trials.
AML with the FLT3-ITD mutation develops due to uncontrollable cell growth within the bone marrow. Quizartinib is an inhibitor drug which specifically targets and restricts the enzyme responsible for this.
The positive decision follows the manufacturer, Daiichi Sankyo, offering a fair price for the treatment that the National Institute for Health and Care Excellence (NICE) determined to be cost-effective and could therefore recommend its use on the NHS in England.
Helen Knight, Director of Medicines Evaluation at NICE, said: “This is a rare and aggressive form of blood cancer with few treatment options. Patients tell us that existing treatments can be very gruelling and that more options would be welcome.
“Clinical evidence found patients taking quizartinib had an average overall survival of almost 32 months compared to just over 15 months for those receiving the placebo, and our independent committee found it to be a cost-effective treatment.
“Our focus is to the ensure the best care for people with this aggressive form of cancer while offering value for money to the taxpayer.
“I am therefore delighted we can recommend it for use on the NHS as a further treatment option that could give people more precious time with their loved ones”.
News
Agetech investment & innovation round-up

Long-term gut health and female finance, London likes longevity
New York innovator Salvo Health has secured $8.5m in Series A round as it looks to develop new, long-term, gut-health treatments.
The funding round was led by ManchesterStory, City Light Capital and Threshold Ventures, with additional support from The Artemis Fund, Owl Capital, Impact X Capital Partners, Torch Capital and Felicis Ventures.
Eric Collins, co-founder and general partner of Impact X Capital Partners, a UK-based venture capital firm, said: “The key with Salvo is patient-centred care.
“It’s critical to expand access to food as medicine and behavioural health to improve outcomes and lower, long-term health care costs.
“Salvo does exactly that and has shown 76 per cent of patients report improved symptoms, with five accepted abstracts on outcomes, and a 79 per cent drop in GI-related ER utilisation for its patients.
“We can have better care at lower costs with innovation, in the US, and ultimately in the UK and Europe as well.”
The raise brings Salvo’s total equity funding to US$21.6m. Roughly 60m Americans experience chronic gastrointestinal conditions each year.
Salvo Health is positioning itself in the space between overburdened clinics and patients’ everyday lives.
Female longevity in focus
Xella Health – a women’s precision platform focused on fertility, ageing, and body changes – has raised over US$3.7m in pre-seed funding.
The funds will support product finalisation, partnerships, and a Spring 2026 launch, focused on sex-specific longevity and preventive care.
The round was led by Precursor Ventures, with participation from Capital F, Ulu Ventures, and other funds, as well as, strategic angel investors across healthcare, diagnostics, and consumer technology.
Xella is aiming to propel women’s health beyond symptom-based care and fragmented testing to deliver ‘integrated biological insight, clarity, and foresight’.
The company combines advanced diagnostics, longitudinal data, and personalised clinician-led guidance to help women understand what’s happening in their bodies today – and what lies ahead – across fertility, chronic conditions, hormonal health, early cancer detection, and preventative care.
“Our mission is to give women the answers and care they have always deserved,” said Kelly Lacob, co-founder & CEO of Xella.
“Xella is building the infrastructure to decode female biology – getting to the root cause of conditions that uniquely, differently or disproportionately affect women, many of which suffer from an unacceptably poor standard of care today.”
“Xella is rethinking women’s health from the ground up – starting with the insight women need to make sense of their own biology over time,” said Ashtan Jordan, principal at Precursor Ventures.
Age well in London
Two London boroughs have launched their own initiatives aimed at supporting their ageing resident populations.
Basildon Council has approved a new Ageing Population Strategy to support older residents live healthy, independent and connected lives.
The number of residents aged 65 and over in Basildon is projected to rise steadily over the next decade, reflecting national longevity trends.
The council says its ‘taking a proactive, preventative approach to ensure Basildon remains an inclusive, accessible and sustainable place for residents of all ages’.
The strategy emphasises strong partnership working with health services, voluntary and community organisations, local businesses and residents.
Key commitments include:
- Supporting people to remain independent in their own homes for longer,
- Promoting age-friendly design in town centres and public spaces,
- Strengthening dementia-friendly communities,
- Expanding opportunities for volunteering and employment, and
- Continuing investment in activity centres and community-led initiatives that reduce loneliness.
Cllr Melissa McGeorge, cabinet member for ageing population & health, said: “Our ambition is clear: to make Basildon a place where people can age well, feel valued, and continue to thrive at every stage of later life.
The ‘Life Curve’
Meanwhile the London Borough of Richmond has launched a new self-assessment tool developed by ADL Research and Newcastle University to help boost longevity.
The ‘Life Curve’ tool is designed to support healthy ageing with personalised advice and practical steps on how to stay active and independent.
Councillor Allen, lead member for adult social care, said: “Getting older doesn’t have to mean we stop being independent and there are small steps we can take to help reduce how getting older limits our lives.
“We have tools and services available in the borough to support residents to take these small daily steps to maintain their health and reduce the risk of conditions like heart disease, cancer and dementia.
“A new tool accessible right from your phone or any other online device is ‘Independent Richmond’, which helps you understand where you are on The Life Curve to help stay on track with healthy habits, keeping active and stay independent for longer.”
News
Bryan Johnson launches US$1m longevity programme

Bryan Johnson has launched a US$1m-a-year longevity programme with just three places, offering access to the exact protocol he has followed for five years.
The programme, called “Immortals”, is offered by the former fintech entrepreneur, now a prominent and often controversial figure in longevity.
Johnson’s unconventional methods have included Botox injections in his genitals (Botox relaxes muscles) and transfusions of blood from his teenage son.
There is no evidence these will help him outlive others.
The “Immortals” package includes a dedicated concierge team, 24/7 access to the BryanAI health coach, extensive testing, continuous tracking of millions of biological data points and what Johnson calls the “best skin and hair protocols.
A lower-cost supported tier is available at US$60,000 per year.
Rivals also target the ultra-wealthy: Biograph’s premium membership costs US$15,000 per year, while Fountain Life’s “ultimate longevity programme” is priced at US$21,500 annually.
Despite the higher price, Johnson’s offer is built on exclusivity, with only three spots available.
News
Cognition and Cera expand Alzheimer’s clinical trials access

Cognition Health and Cera have partnered to expand access to Alzheimer’s clinical trials across the UK.
The collaboration links Re:Cognition Health’s specialist brain health clinics and trial expertise with Cera’s 2.5 million monthly home care visits, creating new pathways to identify and support people earlier in their health journey.
By connecting home care with specialist research centres, the partners aim to offer more people the chance to join studies, giving access to advanced assessment and emerging treatments while contributing to future therapies.
Dr Ben Maruthappu MBE, chief executive and founder of Cera, said: “Many older adults are currently ‘invisible’ to the clinical trials research system because they cannot access traditional clinic-centric recruitment.
“By enabling responsible, consented identification and screening within the home, we can bridge the gap between the community and the clinic.
“We are offering the older generation a seat at the table of global drug discovery, ensuring that the path to a cure starts where they are most comfortable—in their own daily lives.”
Re:Cognition Health has contributed to the development of lecanemab (Leqembi) and donanemab (Kisunla) through international trials, introducing disease-modifying approaches that are reshaping early intervention in Alzheimer’s care.
Older adults remain under-represented in research. NIHR data indicate only about 15 per cent of trial participants are 75 or older, despite high multimorbidity in this group. Dementia trial recruitment in the UK also lags other disease areas.
Through this collaboration, individuals who have not yet accessed specialist memory services can be referred earlier for assessment and potential study participation, with access to new-generation therapies where appropriate.
Cera’s technology-enabled home healthcare model, with daily patient contact and consented data capture, allows timely referral of potential participants from familiar settings to Re:Cognition Health clinics.
Together, the organisations will support earlier and more equitable participation by leveraging Cera’s scale and real-time insights. Carers and nurses deliver visits roughly every second on average, enabling early identification of those who may benefit from memory assessment.
Dr Emer MacSweeney, chief executive and founder of Re:Cognition Health, said: “With one in three people expected to develop dementia in their lifetime, it is essential that we create more inclusive and accessible routes into research.
“This collaboration enables us to extend our reach beyond traditional clinic settings and ensure that people who may benefit from early assessment and research participation are supported to do so.
“Clinical trials offer individuals access to the most advanced diagnostics and emerging treatments, alongside expert medical oversight.
“By identifying people earlier and guiding them through every stage of their journey, we can help improve participants’ experience and potential outcomes, while accelerating the development of the next generation of Alzheimer’s therapies.”
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