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How our bodies break down and remove old and damaged bone tissue is linked to our inner circadian clock, according to a new study. Researchers focused on the processes involved in bone renewal: bone resorption (which allows the body to breakdown and remove old or damaged bone) and bone formation (which builds new bone). The [...]
Any amount of alcohol consumption may increase dementia risk, according to a new large-scale study. The findings challenge the belief that light or moderate drinking might protect brain health, with genetic evidence suggesting harm at all levels. A threefold increase in weekly drinks raised dementia risk by 15 per cent. Scientists combined observational data from [...]
The NHS has warned people not to ignore four key dementia symptoms, stressing they are not just a natural part of getting older. In guidance shared on social media platform X, the health service said that memory loss, difficulty concentrating, struggling with familiar tasks and mood changes could indicate cognitive decline rather than normal ageing. [...]
Agetech world explores the latest business and investment developments in the world of ageing and longevity. Joint venture to advance Klotho-based therapies Nevada-based Avant Technologies and Singapore-based biotech company Austrianova are entering into a joint venture and license agreement to establish Klothonova - a new company focused on pioneering cell-based therapies utilising encapsulated Klotho-producing cells. [...]
Scientists have uncovered a mechanism that could lead to treatments aimed at reversing osteoporosis rather than only slowing its progression. The finding involves a cell receptor called GPR133, also known as ADGRD1, which regulates osteoblasts – the cells that build new bone tissue. When triggered by a compound called AP503, this receptor increased bone strength [...]
Cycling instead of driving or taking public transport is linked to a 19 per cent lower risk of developing dementia. An analysis of nearly 480,000 people in Great Britain also found regular cyclists had a 22 per cent lower risk of Alzheimer’s disease compared with those using cars, buses or trains. More than 55m people [...]
Vigorous physical activity lowers levels of a blood protein tied to dementia risk and brain inflammation, new research has found. Almost 1.1m people are predicted to have dementia by 2065 – a 2.5-fold increase. Scientists at the University of Tasmania’s Wicking Dementia Research and Education Centre reported that exercise reduces levels of GFAP (glial fibrillary [...]
Chronic insomnia may accelerate brain ageing by three years and raises dementia risk by 40 per cent, according to new research. The study tracked 2,750 cognitively healthy older adults with an average age of 70 for more than five and a half years. Those with the sleep disorder were far more likely to develop cognitive [...]
A new pill being tested could halt dementia progression and reverse the brain’s biological age by a decade, according to its developers. The treatment, called RTR242, works by reviving the brain’s natural cleaning system to clear harmful protein clumps that build up with age. Such clumps are linked to Alzheimer’s, Parkinson’s and Lewy body dementia. [...]
Adults who use cannabis are nearly four times more likely to develop type 2 diabetes than non-users, a major study has found. The research analysed about 96,800 people with cannabis-related diagnoses – from casual use to dependency – and compared them with more than 4.16m individuals who had no record of drug use or chronic [...]
