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Swapping just 30 minutes of sitting for light activity, such as walking or housework, can improve mood and energy the following day, new research suggests. A study involving more than 350 young adults found that on days when participants spent less time sitting and more time doing light activity, they felt happier and more energised [...]
Bright light at night raises the risk of heart attack by 47 per cent and heart failure by 56 per cent, according to research involving nearly 89,000 people. Being exposed to bright light at night could significantly increase the chances of developing serious heart problems, including heart attacks, strokes and heart failure. The largest study [...]
Generation Lab has raised US$11m to expand its SystemAge platform for ageing diagnostics and clinic rollout, less than a year after launch. The seed round, led by Accel, brings total funding to US$15m. Other backers include Samsung Next, Zone2, Aoki Labs, BYL Ventures and Markham Valley Ventures. SystemAge estimates biological age — how well body [...]
Semaglutide reduces the risk of heart attack and stroke by 20 per cent, regardless of weight lost, according to the largest study of 17,604 patients. The drug, the main ingredient in Wegovy, reduced the risk of major adverse cardiac events — including deaths from heart disease, heart attacks or strokes — by 20 per cent, [...]
Researchers have shown that new TOR inhibitor rapalink-1 prolongs lifespan in fission yeast, offering insight into how drugs may slow ageing. Rapalink-1, a next-generation TOR inhibitor currently under investigation for cancer therapy, slowed cell growth and significantly extended lifespan in yeast models, acting through TORC1 — the growth-promoting arm of the TOR pathway. The TOR [...]
Researchers in Denmark have discovered why the APOE4 gene increases Alzheimer’s risk — by preventing brain cells from switching from glucose to fats for energy as they age. The study found that as brain cells grow older and lose efficiency in using glucose — their main energy source — they can normally switch to burning [...]
Nearly half of 18 to 24-year-olds in the UK fear developing dementia, compared with just over a third of those aged over 65, new research has found. The study, commissioned by Bluebird Care, found that 45 per cent of those aged 18 to 24 expressed concern about developing the condition. This makes them the most [...]
The Mediterranean diet can reduce the risk of gum disease and inflammation by up to 65 per cent, according to new research. The diet, rich in fruit, vegetables, legumes and olive oil, was found to lower inflammation linked to gum disease. Gum disease, also called periodontal disease, affects the tissues supporting teeth and can lead [...]
The wife of a Rotherham man with dementia is supporting a £250,000 campaign to make hospital wards more dementia-friendly. Wendy Parker, 60, from Rotherham, cares for her husband Jonathon, who was diagnosed with early-onset dementia at 59. She said typical hospital settings can be “frightening and confusing” for patients. Early-onset dementia means symptoms appear before [...]
NewLimit has secured an extra US$45m on a US$1.62bn valuation to advance epigenetic reprogramming medicines and prepare for a first clinical study in the coming years. The company is developing therapies to restore youthful function in older cells. Epigenetic reprogramming aims to reset chemical “tags” on DNA and its packaging proteins, restoring healthier gene activity [...]
