Research
Many recent studies assume that elderly people are at particular risk of dying from extreme heat as the planet warms. However, a new study of mortality in Mexico turns this assumption on its head: it shows that 75 per cent of heat-related deaths are occurring among people under 35―a large percentage of them ages 18 [...]
Redlining—a mid-20th-century federal government practice of denying home loans in African American and other minority neighbourhoods in the US—has long been associated with poor health outcomes, including disparate overall mortality rates among racial and ethnic groups. The term gets its name from the practice by the Home Owners’ Loan Corporation (HOLC, operational from 1933 to [...]
Researchers have discovered that accumulated DNA damage in the retina is a key contributor to age-related macular degeneration and that targeting specific retinal cell types may lead to treatments that slow or stop progression. AMD is a major cause of blindness in people over 50. It exists in two forms: wet, which is treated with [...]
Researchers will explore a system that uses light for non-invasive monitoring of Alzheimer’s Disease. The system will use single-pixel imaging to measure activity in the brain, and the researchers aim to complement existing technology by enhancing its fidelity while also making the process safer and less expensive. A technique currently used in brain imaging, known [...]
A minimally invasive procedure provides significant relief from knee pain and may prevent the need for knee replacement surgery in people with osteoarthritis, according to a new study. Osteoarthritis, a chronic, degenerative and progressive condition, is the most common cause of chronic joint disorders. According to the World Health Organization, knee osteoarthritis affects over 365 [...]
An experimental study in mice shows that SARS-CoV-2 infection can damage the retinas, with long-term implications for vision. Post-acute sequelae of SARS-CoV-2 infection include various neurocognitive symptoms, suggesting the virus can affect the central nervous system. The eyes are also part of the central nervous system, but little is known about the virus’s effects on [...]
Oxford Nanopore Technologies has entered into a new collaboration with UK Biobank to create the world’s first comprehensive, large-scale epigenetic dataset that targets cancer, dementia, and complex diseases. The project will utilise Oxford Nanopore’s information-rich DNA/RNA sequencing technology to map the epigenome of 50,000 participant samples to unlock crucial insights into disease mechanisms, with the [...]
Researchers have shed new light on how mechanical signalling in the brain is disrupted and could lead to the condition which accounts for 60 to 80 per cent of dementia cases worldwide. The researchers examined the role of two proteins found in the brain and suggest the stability of their relationship to one another is [...]
A new study has revealed that ageing specifically impairs the generation of CD8+ tissue resident memory T cells (TRM) and thus compromises the antitumor defensive activity of aged CD8+ T cells. With the ageing process, the risk of developing cancer significantly increases. In recent years, it has been reported that immune aging has an important [...]
Men with cardiovascular disease risk factors, including obesity, face brain health decline a decade earlier—from their mid 50s to mid 70s—than similarly affected women who are most susceptible from their mid 60s to mid 70s, suggest the findings of a long term study. The most vulnerable regions of the brain are those involved in processing [...]
