Research
Limiting the PTP1B enzyme could slow memory loss in Alzheimer's, pointing to a potential treatment route, new research suggests. The enzyme appears to contribute to memory decline in mice by altering how the brain's immune cells behave, researchers say. Dialling down PTP1B let microglia clear the protein clumps linked to Alzheimer's, known as amyloid-beta plaques. [...]
We round up the latest news in agetech research and innovation, from a human trial in ‘reverse ageing’ to the launch of a domestic longevity pod. Approval has been secured in the United States for the first human trial targeting ‘reverse ageing’. Boston-based company Life Biosciences will shortly commence trials of its ER-100 treatment which [...]
Up to four in ten cancer cases worldwide could be prevented, a new global analysis has found. The study examines 30 preventable causes, including tobacco, alcohol, high body mass index, physical inactivity, air pollution, ultraviolet radiation and, for the first time, nine infections that can cause the disease. Released ahead of World Cancer Day on [...]
A 25-year Swedish study links higher cheese intake to lower Alzheimer's risk in people without known genetic risk, with cream also tied to lower dementia risk. However, researchers emphasise that the results should be interpreted with caution. The study tracked 27,670 people over 25 years. During that time, 3,208 participants were diagnosed with dementia. Among [...]
Memory problems in Alzheimer's may be linked to disrupted brain replay during rest, new research suggests. The study, conducted in mice, points to a disrupted brain process that normally helps strengthen and preserve memories. Researchers say the findings could inform future drugs that target this malfunctioning process and guide tools for earlier detection. Scientists at [...]
Scientists have developed a pancreatic cancer blood test that could detect disease earlier, potentially improving survival if validated in larger studies. Around 10,500 people are diagnosed with the disease in the UK each year, but it is hard to treat and diagnose. Because it is often found late, only 10 per cent live longer than [...]
Key developments in biologics and technology are paving the way for a future in which degenerative diseases - such as Alzheimer's and Parkinson’s - can be identified and nullified before their onset. US physician Dr Annu Navani is driving these developments, which she believes will allow mankind to develop ‘the power to recode life itself’. [...]
A new study says CTE should be recognised as a cause of dementia, with those in the most advanced stages facing a 4.5-fold higher lifetime risk. Chronic traumatic encephalopathy (CTE) is a degenerative brain condition seen in some athletes. Linked to repeated head impacts, it can cause memory loss, mood changes, poor coordination and suicidal [...]
A UK university will become one of the first in the country to make improving the health and well-being of the elderly one of its six ‘mission-led’ research priorities. Bournemouth University’s choice to focus on pensioners is partly the result of the Labour Government's wish for universities to specialise, whilst also reflecting the area’s demographics [...]
New research links gut inflammation to Alzheimer's, with higher levels associated with more amyloid plaque in the brain. Animal studies have shown Alzheimer's can be passed to young mice through gut microbe transfer, strengthening the link between the gut and the brain. A 2023 study adds support to inflammation as a possible mechanism. Barbara Bendlin, [...]
