News
Korsana Biosciences has emerged from stealth with US$175m to develop an Alzheimer’s antibody designed to boost amyloid plaque clearance. The Waltham, Massachusetts-based biotech is focused on neurodegenerative disease. Its lead programme, KRSA-028, is a next-generation shuttled monoclonal antibody targeting amyloid beta, a protein that can build up into plaques in Alzheimer’s. The treatment uses the [...]
Regenerative innovator's cash boost, are biological clocks out of time?, Y chromosome concerns, £60bn of graft by UK pensioners Indian regenerative medicine company Pandorum Technologies, has raised US$18m in a Series B funding round to support its clinical developments and global expansion. The company, which operates the United States as well as its domestic market, [...]
GSK has signed a five-year deal with JAX-NYSCF to build stem cell models for neurodegenerative disease, with Alzheimer’s a key target. The collaboration with The Jackson Laboratory-New York Stem Cell Foundation Collaborative aims to combine human stem cell research with large-scale research systems to help bridge discovery and drug development. The partners plan to develop [...]
Long-term air pollution exposure may raise Alzheimer’s risk mainly through direct effects on the brain, a study of US Medicare records suggests. The research followed more than 27.8m US Medicare recipients aged 65 and over from 2000 to 2018, comparing estimated pollution exposure with later Alzheimer’s diagnoses. Researchers focused on PM2.5, very fine particles smaller [...]
An AI model using gait data before and after hip replacement could help predict which patients will walk close to normal and who may need extra rehabilitation. The tool analyses gait biomechanics, the study of how people walk, using data collected before and after operations in people with hip osteoarthritis, caused by cartilage wear in [...]
Ageing should be central to Parkinson’s research, experts argue, saying it has been sidelined as studies focused on genetics and single disease mechanisms. Parkinson’s is a progressive neurological condition that affects movement and can cause tremors, stiffness and balance problems. It affects about one million people in the US and more than ten million worldwide, [...]
Traditional dal bhat could help curb Nepal’s diabetes crisis, with one in five people over 40 living with type 2 diabetes, researchers say. With medication often unaffordable, researchers are testing whether cheap, local staples such as lentils and rice can help tackle type 2 diabetes, where blood sugar stays high because the body does not [...]
Processing-speed brain training with booster sessions was linked to a lower dementia diagnosis risk over 20 years, according to a long follow-up study. The findings come from extended tracking of a large randomised controlled trial, where participants were assigned by chance to different training programmes or no intervention. Researchers linked trial records to US Medicare [...]
Long-term gut health and female finance, London likes longevity New York innovator Salvo Health has secured $8.5m in Series A round as it looks to develop new, long-term, gut-health treatments. The funding round was led by ManchesterStory, City Light Capital and Threshold Ventures, with additional support from The Artemis Fund, Owl Capital, Impact X Capital [...]
Bryan Johnson has launched a US$1m-a-year longevity programme with just three places, offering access to the exact protocol he has followed for five years. The programme, called "Immortals", is offered by the former fintech entrepreneur, now a prominent and often controversial figure in longevity. Johnson’s unconventional methods have included Botox injections in his genitals (Botox [...]
