Medtech / devices
A Cambridge-based biotech firm has identified a novel single-gene target that may rejuvenate cells without triggering cancer, potentially enabling safer anti-ageing therapies. The discovery, known as SB000, is claimed to reverse signs of cellular ageing across multiple cell types—without activating the harmful biological pathways associated with other methods. Shift Bioscience, which is developing therapies for [...]
A new blood test for Alzheimer’s disease can accurately identify people with early symptoms by examining two key proteins in blood plasma. The test, which has been approved by the US Food and Drug Administration (FDA), showed 95 per cent sensitivity in picking up people with memory problems—meaning it correctly identified the vast majority of [...]
A home device that scans a person’s feet as soon as they get out of bed in the morning could help keep people with heart failure out of hospital, according to new research. More than a million people in the UK have heart failure, which—when not fully managed by medication or lifestyle changes—can lead to [...]
Apple Watches and similar wearable devices exhibit significant inaccuracies when estimating calories burned, despite performing well in monitoring heart rate and counting steps. A comprehensive review of 56 studies conducted by researchers at the University of Mississippi found that while fitness trackers are generally reliable for basic metrics, they struggle with energy expenditure calculations—a key [...]
Researchers have released the full dataset from a decade-long project designed to track brain and cognitive health as people age and distinguish neurologically healthy paths from those indicating a likelihood of decline. The Dallas Lifespan Brain Study (DLBS) combined brain and cognition measures across the adult lifetime, including an expansive range of imaging and tests [...]
New research has revealed that phase angle - a measure of muscle quality - is linked to memory performance and dementia risk in middle-aged and older adults. Over the past decade, much research has focused on the connection between skeletal muscle health and cognitive disorders. Scientists have found that sarcopenia, a geriatric syndrome characterised by progressive loss [...]
There is increasing interest in finding drugs, known as gerotherapeutics, that can slow ageing and help people live longer. Now, metformin, a common diabetes drug, is being studied because it affects several ageing-related processes. In a multi-institutional study, researchers examined the relationship between metformin use and a longer lifespan among postmenopausal women with type 2 [...]
As people age, their immune systems become less efficient, posing a challenge for cancer therapies that rely on harnessing immune cells. In a new study published in Nature Cancer, researchers from the University of Lausanne (UNIL), the Lausanne University Hospital (CHUV), the Geneva University Hospitals (HUG) and the Ecole Polytechnique Fédérale de Lausanne (EPFL), show [...]
A team of researchers have discovered that microscopic structural changes in the ageing heart may reduce the risk of irregular heartbeats. Medically known as arrhythmias, irregular heartbeats become more common with age and can lead to health problems. But a new study, carried out by Virginia Tech researchers at the Fralin Biomedical Research Institute at VTC, revealed [...]
A new study has demonstrated that artificial intelligence can be used not just to accelerate drug discovery, but to fundamentally transform how it’s done - by targeting the full complexity of biological ageing. In a collaboration between Scripps Research and Gero, a biotechnology company focused on ageing, scientists developed a machine learning model trained to [...]
