Biotech & life science
Ageing cells may help trigger unstable plaques in blood vessels linked to heart attacks and strokes, preclinical research suggests. The findings could help explain how disturbed blood flow contributes to plaques becoming dangerous and forming clots. They may also shed light on cardiovascular side effects linked to some cancer treatments, which can accelerate cellular ageing. [...]
New models may improve Alzheimer's research in people with Down syndrome and help test whether emerging treatments are safe. The work aims to address a major gap in Alzheimer's studies, as people with Down syndrome are often excluded from clinical trials despite their greatly increased risk. Around 6m people globally live with Down syndrome, and [...]
An experimental molecule may partly restore the brain's defences against Alzheimer's by reprogramming immune cells, a new study suggests. The compound, called OLE, helped microglia enclose and contain beta-amyloid plaques, reducing their size and toxicity. In animal models, the treatment also improved cognitive performance in memory tests. Researchers led by José Vicente Sánchez Mut at [...]
An AI blood test may help identify four dementia-linked brain diseases with 92.3 per cent accuracy, researchers say. Many people living with dementia never receive an accurate diagnosis, partly because Alzheimer's disease, Parkinson's disease and related conditions can be hard to tell apart and often occur together. The tool is designed to distinguish Alzheimer's disease, [...]
LONGEVITY science is entering the mainstream with the launch of the world’s first healthspan PhD and the creation of the world’s first ‘longevity board’ for AI-enabled research. Switzerland’s Geneva College of Longevity Science (GCLS) and its Romanian partner Ovidius University of Constanța say their four-year PhD doctoral programme represents a milestone in the evolution of [...]
Alzheimer’s drug pioneer Anavex is pressing ahead with plans to secure approval for its ground-breaking treatment despite a recent setback. Earlier this year it lodged an appeal against the European Medicines Agency (EMA) decision to reject its application for drug approval in December 2025. But, Anavex has now withdrawn this appeal as it seeks to [...]
This month Agetech World is focusing on the future. What does healthy lifespan look like, and how long can it last? Our introductory article in this special series looks at the ‘biohacking’ quest to re-engineer ageing - and who it will benefit? Click below to read Agetech World editor Peter McCusker's report now. [...]
