Connect with us

News

People with critical cardiovascular disease may benefit from palliative care

Published

on

Palliative care may help relieve symptoms and improve quality of life for people with cardiovascular disease and ensure that treatment is aligned with the patient’s personal beliefs and values throughout all stages of illness, according to a new American Heart Association scientific statement.

This applies whether they are hospitalised in a cardiac intensive care unit or receiving outpatient care, says the statement.

The new scientific statement, “Palliative and End-of-Life Care During Critical Cardiovascular Illness,” suggests strategies to integrate palliative care principles into the management of patients with critical cardiovascular illness.

Palliative care aims to improve quality of life; to minimise physical, emotional and spiritual distress; to facilitate complex discussions regarding prognosis and goals of care; and to provide emotional and psychosocial support to patients, family members and caregivers throughout all stages of illness, not just at the end of life.

Currently, palliative care is most widely used caring for patients with cancer.

“We need to better understand the benefits of palliative care in a broad range of cardiovascular conditions and particularly for patients with acute, critical illness,” said volunteer Chair of the scientific statement writing group Erin Bohula, an assistant professor of medicine at Harvard Medical School and critical care cardiologist at Brigham & Women’s Hospital, both in Boston.

“People with a variety of heart conditions face increasing symptoms, functional limitations and a need to align care with their personal preferences, beliefs and values – whether that’s to do everything possible or to prioritise comfort and quality of life. A patient-centred approach needs to be considered, particularly when making decisions about available and sometimes invasive care options as their condition advances.”

The statement authors emphasise that palliative care can be provided in addition to evidence-based treatments at any stage of a person’s illness, from intensive care to outpatient care.

However, providing palliative care for cardiovascular disease can be challenging because the progression of the illness can be unpredictable, and there may be sudden, urgent situations requiring hospitalisation and/or admission to the cardiac intensive care unit.
These can result in new symptoms such as loss in physical function and may lead to unexpected end-of-life situations that necessitate more intensive support from cardiology and palliative care professionals.

In addition, many patients admitted to cardiac intensive care units are older (with a median age of 65 years), more frail and critically ill, with advanced and complex cardiovascular conditions, and they may also have multiple non-cardiac conditions.

Palliative care health professionals need to be knowledgeable about the medical prognosis and quick decision-making required in cardiac intensive care units, including the management of life-sustaining technologies and advanced cardiac interventions.

Palliative care can be integrated into care to manage symptoms and improve quality of life for patients with different types of cardiovascular disease, says the statement.

Despite the growing evidence about the benefits of palliative care, many people with cardiovascular disease have limited access to palliative care specialists. Rates of referral to palliative care for patients with cardiovascular disease are low and often delayed compared to patients with cancer.

Due to delayed referrals and the scarcity of palliative care resources, it can be difficult for individuals with cardiovascular disease to access outpatient palliative care. Inpatient palliative care services may also be limited in settings outside of large hospitals.

The statement suggests integrating palliative care services into heart failure clinics and post-discharge services for patients recently hospitalised in the cardiac intensive care unit, creating a transition from inpatient to outpatient care.

There are also complex ethical considerations for patients with advanced cardiovascular disease, particularly in relation to life-sustaining interventions.

Medical codes of ethics emphasise promoting patient well-being, avoiding harm and respecting patient autonomy; however, these can sometimes seem at odds in the setting of the cardiac intensive care unit or treating a patient with end-stage cardiovascular disease.

For example, deactivating the shocking function of an implanted cardiac defibrillator may increase the risk of death if a fatal arrhythmia occurs, while at the same time minimising a patient’s pain by avoiding the delivery of multiple shocks.

A separate, recently published American Heart Association scientific statement on palliative care and advanced cardiovascular disease highlights the importance of shared decision-making involving the patient and family as the disease progresses.

When a patient’s symptoms become more severe and difficult to manage, discussions about changing or discontinuing certain treatments may be necessary based on the patient’s personal preferences, quality of life, prognosis and advanced care documents.

Education for cardiovascular specialists
While palliative care is not a recognised subspecialty of cardiology, its approaches can be offered by cardiovascular clinicians with specialized training in palliative care and in consultation with palliative care specialists. However, only a small fraction of health care professionals who complete a cardiology fellowship receive either required or elective training in palliative care.

The scientific statement also identifies several basic palliative care.

“It is critical that all cardiac intensive care unit and acute care professionals have the tools and knowledge to provide the basic tenets of palliative care, such as symptom management and ensuring that care is appropriate and aligns with the patient’s personal choices. As the field of cardiac critical care advances, incorporating palliative care principles ensures a holistic approach to providing care and addressing the complex needs of these patients during a health care crisis or at the end-of-life,” said Bohula.

 

Continue Reading
Click to comment

Leave a Reply

Your email address will not be published. Required fields are marked *

News

Agetech investment & innovation round-up

Published

on

Two London boroughs have launched their own initiatives aimed at supporting their ageing resident populations. 

Long-term gut health and female finance, London likes longevity

New York innovator Salvo Health has secured $8.5m in Series A round as it looks to develop new, long-term, gut-health treatments.

The funding round was led by ManchesterStory, City Light Capital and Threshold Ventures, with additional support from The Artemis Fund, Owl Capital, Impact X Capital Partners, Torch Capital and Felicis Ventures. 

Eric Collins, co-founder and general partner of Impact X Capital Partners, a UK-based venture capital firm, said: “The key with Salvo is patient-centred care.

“It’s critical to expand access to food as medicine and behavioural health to improve outcomes and lower, long-term health care costs.

“Salvo does exactly that and has shown 76 per cent of patients report improved symptoms, with five accepted abstracts on outcomes, and a 79 per cent drop in GI-related ER utilisation for its patients.

“We can have better care at lower costs with innovation, in the US, and ultimately in the UK and Europe as well.”

The raise brings Salvo’s total equity funding to US$21.6m. Roughly 60m Americans experience chronic gastrointestinal conditions each year.

Salvo Health is positioning itself in the space between overburdened clinics and patients’ everyday lives.

Female longevity in focus

Xella Health – a women’s precision platform focused on fertility, ageing, and body changes – has raised over US$3.7m in pre-seed funding.

The funds will support product finalisation, partnerships, and a Spring 2026 launch, focused on sex-specific longevity and preventive care.

The round was led by Precursor Ventures, with participation from Capital F, Ulu Ventures, and other funds, as well as, strategic angel investors across healthcare, diagnostics, and consumer technology.

Xella is aiming to propel women’s health beyond symptom-based care and fragmented testing to deliver ‘integrated biological insight, clarity, and foresight’. 

The company combines advanced diagnostics, longitudinal data, and personalised clinician-led guidance to help women understand what’s happening in their bodies today – and what lies ahead – across fertility, chronic conditions, hormonal health, early cancer detection, and preventative care.

“Our mission is to give women the answers and care they have always deserved,” said Kelly Lacob, co-founder & CEO of Xella.

“Xella is building the infrastructure to decode female biology – getting to the root cause of conditions that uniquely, differently or disproportionately affect women, many of which suffer from an unacceptably poor standard of care today.”

“Xella is rethinking women’s health from the ground up – starting with the insight women need to make sense of their own biology over time,” said Ashtan Jordan, principal at Precursor Ventures. 

Age well in London

Two London boroughs have launched their own initiatives aimed at supporting their ageing resident populations. 

Basildon Council has approved a new Ageing Population Strategy to support older residents live healthy, independent and connected lives.

The number of residents aged 65 and over in Basildon is projected to rise steadily over the next decade, reflecting national longevity trends.

The council says its ‘taking a proactive, preventative approach to ensure Basildon remains an inclusive, accessible and sustainable place for residents of all ages’.

The strategy emphasises strong partnership working with health services, voluntary and community organisations, local businesses and residents.

Key commitments include:

  •       Supporting people to remain independent in their own homes for longer,
  •       Promoting age-friendly design in town centres and public spaces,
  •       Strengthening dementia-friendly communities,
  •       Expanding opportunities for volunteering and employment, and
  •       Continuing investment in activity centres and community-led initiatives that reduce loneliness.

Cllr Melissa McGeorge, cabinet member for ageing population & health, said: “Our ambition is clear: to make Basildon a place where people can age well, feel valued, and continue to thrive at every stage of later life.

The ‘Life Curve’

Meanwhile the London Borough of Richmond has launched a new self-assessment tool developed by ADL Research and Newcastle University to help boost longevity.

The ‘Life Curve’ tool is designed to support healthy ageing with personalised advice and practical steps on how to stay active and independent.

Councillor Allen, lead member for adult social care, said: “Getting older doesn’t have to mean we stop being independent and there are small steps we can take to help reduce how getting older limits our lives.

“We have tools and services available in the borough to support residents to take these small daily steps to maintain their health and reduce the risk of conditions like heart disease, cancer and dementia. 

“A new tool accessible right from your phone or any other online device is ‘Independent Richmond’, which helps you understand where you are on The Life Curve to help stay on track with healthy habits, keeping active and stay independent for longer.” 

 

Continue Reading

News

Bryan Johnson launches US$1m longevity programme

Published

on

Bryan Johnson has launched a US$1m-a-year longevity programme with just three places, offering access to the exact protocol he has followed for five years.

The programme, called “Immortals”, is offered by the former fintech entrepreneur, now a prominent and often controversial figure in longevity.

Johnson’s unconventional methods have included Botox injections in his genitals (Botox relaxes muscles) and transfusions of blood from his teenage son.

There is no evidence these will help him outlive others.

The “Immortals” package includes a dedicated concierge team, 24/7 access to the BryanAI health coach, extensive testing, continuous tracking of millions of biological data points and what Johnson calls the “best skin and hair protocols.

A lower-cost supported tier is available at US$60,000 per year.

Rivals also target the ultra-wealthy: Biograph’s premium membership costs US$15,000 per year, while Fountain Life’s “ultimate longevity programme” is priced at US$21,500 annually.

Despite the higher price, Johnson’s offer is built on exclusivity, with only three spots available.

Continue Reading

News

Cognition and Cera expand Alzheimer’s clinical trials access

Published

on

Cognition Health and Cera have partnered to expand access to Alzheimer’s clinical trials across the UK.

The collaboration links Re:Cognition Health’s specialist brain health clinics and trial expertise with Cera’s 2.5 million monthly home care visits, creating new pathways to identify and support people earlier in their health journey.

By connecting home care with specialist research centres, the partners aim to offer more people the chance to join studies, giving access to advanced assessment and emerging treatments while contributing to future therapies.

Dr Ben Maruthappu MBE, chief executive and founder of Cera, said: “Many older adults are currently ‘invisible’ to the clinical trials research system because they cannot access traditional clinic-centric recruitment.

“By enabling responsible, consented identification and screening within the home, we can bridge the gap between the community and the clinic.

“We are offering the older generation a seat at the table of global drug discovery, ensuring that the path to a cure starts where they are most comfortable—in their own daily lives.”

Re:Cognition Health has contributed to the development of lecanemab (Leqembi) and donanemab (Kisunla) through international trials, introducing disease-modifying approaches that are reshaping early intervention in Alzheimer’s care.

Older adults remain under-represented in research. NIHR data indicate only about 15 per cent of trial participants are 75 or older, despite high multimorbidity in this group. Dementia trial recruitment in the UK also lags other disease areas.

Through this collaboration, individuals who have not yet accessed specialist memory services can be referred earlier for assessment and potential study participation, with access to new-generation therapies where appropriate.

Cera’s technology-enabled home healthcare model, with daily patient contact and consented data capture, allows timely referral of potential participants from familiar settings to Re:Cognition Health clinics.

Together, the organisations will support earlier and more equitable participation by leveraging Cera’s scale and real-time insights. Carers and nurses deliver visits roughly every second on average, enabling early identification of those who may benefit from memory assessment.

Dr Emer MacSweeney, chief executive and founder of Re:Cognition Health, said: “With one in three people expected to develop dementia in their lifetime, it is essential that we create more inclusive and accessible routes into research.

“This collaboration enables us to extend our reach beyond traditional clinic settings and ensure that people who may benefit from early assessment and research participation are supported to do so.

“Clinical trials offer individuals access to the most advanced diagnostics and emerging treatments, alongside expert medical oversight.

“By identifying people earlier and guiding them through every stage of their journey, we can help improve participants’ experience and potential outcomes, while accelerating the development of the next generation of Alzheimer’s therapies.”

Continue Reading

Trending

Agetech World