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A new study of nearly a million emergency admissions in Norway has found increased mortality in the elderly who live in the countryside compared to those that live in the city. Research shows that elderly people living in rural areas have higher mortality rates if they are discharged to a municipality under pressure. Additionally, the [...]
A new probe aimed at gaining a better understanding of the ageing process to help shape treatments that could reverse degenerative processes has been launched. Researchers are focusing in on one of the hallmarks of ageing - the increased frequency of senescent cells in most organs, leading to tissue dysfunction. The presence of these cells [...]
Researchers from Amsterdam UMC Cancer Center Amsterdam have looked at inequalities in access to early-stage lung cancer care in Europe. Early-stage lung cancer has stark differences between European countries regarding access and reimbursement. There are also differences in reimbursement times and indications between the European Medicines Agency (EMA) and the US Food and Drug Administration [...]
A new paper has examined the relationship between childhood adversity and psychiatric decline, as well as adult adversity and psychiatric and cognitive decline. The findings revealed just one instance of adversity in childhood can increase cases of mental illness later in life. It also revealed that adverse events in adults can lead to a greater [...]
A new, in-vehicle sensing system could provide the first step toward widespread, low-cost early warnings of cognitive change among older drivers in the US and elsewhere. An estimated 4 to 8 million older adults with mild cognitive impairment are currently driving in the United States, and one-third of them will develop dementia within five years. [...]
Sitting for long hours without breaks can increase risk mortality risk in older women, a new study shows. The research, published in the Journal of the American Heart Association (JAHA), has data showing that older women who sat for 11.7 hours or more per day increased their risk of death by 30 percent, regardless of whether [...]
A study finds an increased risk of hospital readmission for older Americans within 180 days of undergoing major surgery — a risk that is particularly acute for individuals who are frail or have dementia. The findings from researchers at the University of Yale, were published in the journal JAMA Network Open. Previous research by the same [...]
A study conducted by researchers at the Federal University of São Carlos (UFSCar) in Brazil and University College London (UCL), found the factors that increase the risk of frailty in old age to be different in men and women. The study, which was funded by FAPESP, is published in the journal Archives of Gerontology and Geriatrics. According [...]
A new screening tool has been developed that will investigate the mechanisms behind conditions such as cancer, arthritis, neurodegeneration and cardiovascular disease. Wellcome Sanger Institute researchers and their collaborators at Open Targets and EMBL’s European Bioinformatics Institute (EMBL-EBI) have developed the screening tool called scSNV-seq. The tool has been designed to uncover how genetic changes [...]
A new study has determined the protective role of the vitamin D/vitamin D receptor pathway in differentiated enterocytes (ECs) during intestinal stem cell (ISC) aging. Adult stem cells are pivotal for maintaining tissue homeostasis. Their functional decline is linked to aging and associated diseases, influenced by the cells’ environment. Age- and cancer-related reduction of vitamin [...]
