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The first comprehensive cell atlas of ageing human muscle reveals the intricate genetic and cellular processes behind muscle deterioration and mechanisms to counteract it. How muscle changes with ageing, and tries to fight its effects, is now better understood at the cellular and molecular level with the first comprehensive atlas of ageing muscles in humans. [...]
The British Society for Research on Ageing (BSRA) is calling for more public backing in the UK for research to help people stay healthier for longer, as an alternative to charities that support research on diseases. The greatest risk factor for disease is ageing, but we have very little charitable support for research into how [...]
A new study of 7,000 people age 55-plus has found they're staying at home more and skipping restaurants, the gym and other 'third places', since the Covid-19 pandemic. Years after the US began to slowly emerge from mandatory Covid-19 lockdowns, more than half of older adults still spend more time at home and less time [...]
MSU researchers have concluded that little is being done to address the prevalence of early knee osteoarthritis (OA) symptoms faced by patients after anterior cruciate ligament (ACL) reconstruction, calling for more action. Scholars from Michigan State University’s Department of Kinesiology have published a new study in the Journal of Athletic Training in January showing these [...]
In the realm of aged bone repair, materiobiology emphasises the meticulous modulation and restoration of biological functions at various levels — cellular, tissue, organ, and organism — through the use of functionalized biomaterials. In the elderly, a multitude of factors contribute to diminished bone regeneration capabilities. These include a reduction in the self-renewal and differentiation [...]
A new study has found that accelerated ageing was more common in recent birth cohorts and was associated with increased incidence of early-onset solid tumours. Researchers from Washington University School of Medicine in St. Louis hypothesised that increased biological age, indicative of accelerated ageing, may contribute to the development of early-onset cancers. These cancers are [...]
Global life expectancy has increased by 6.2 years since 1990 according to a new study published in The Lancet, as the world addressed major killers including diarrhoea, lower respiratory infections, and stroke. Over the past three decades, reductions in death from leading killers fuelled this progress, including diarrhoea and lower respiratory infections, as well as [...]
New findings could bring us closer to understanding how canine (and human) cognition is organised, and how cognitive decline progresses with age. In their new study, researchers at the Department of Ethology at Eötvös Loránd University (ELTE) discovered that dogs may possess a key component of intelligence known as the 'g factor'. This shares many [...]
Hevolution Foundation has announced its first life science impact investment of $20 million to help Aeovian Pharmaceuticals advance its innovative platform of selective mTORC1 inhibitors which could lead to several promising therapies for disease of ageing. The investment was the leading contribution in a $50 million Series A financing extension for Aeovian. Evolution Foundation has [...]
Biomedical engineers are collaborating with orthopaedic surgeons to build a living replacement knee which could be tested in clinical trials within the next five years. A team of researchers from Columbia University Irving Medical Center (CUIMC) and Columbia Engineering has been awarded up to a $38.95 million contract from the Advanced Research Projects Agency for Health (ARPA-H) to build a living [...]
