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Klothea Bio has secured funding from Longevitytech.fund to pioneer breakthrough treatments for metabolic syndrome and several age-related diseases. Advantage Therapeutics, which develops therapies targeting age-related diseases, has announced the formation of its new subsidiary, Klothea Bio, which will focus exclusively on the research and development of klotho-based therapies to prevent and treat various age-associated conditions. [...]
Researchers have shed new light on how mechanical signalling in the brain is disrupted and could lead to the condition which accounts for 60 to 80 per cent of dementia cases worldwide. The researchers examined the role of two proteins found in the brain and suggest the stability of their relationship to one another is [...]
A study has found that certain hormone replacement therapy (HRT) tablets containing both oestrogen and progestogen are associated with a higher risk of heart disease and rare but serious blood clots known as venous thromboembolism (VTE) in women around the age of menopause. Another HRT tablet called tibolone was associated with an increased risk of [...]
A new study has revealed that ageing specifically impairs the generation of CD8+ tissue resident memory T cells (TRM) and thus compromises the antitumor defensive activity of aged CD8+ T cells. With the ageing process, the risk of developing cancer significantly increases. In recent years, it has been reported that immune aging has an important [...]
Early detection of cognitive impairment is essential for improving patient outcomes, but primary care settings face significant challenges in screening. A new report summarises key points and gaps in knowledge about methods for detecting cognitive impairment in primary care clinics. The report highlights the importance of addressing the rising incidence of cognitive impairment as the [...]
Men with cardiovascular disease risk factors, including obesity, face brain health decline a decade earlier—from their mid 50s to mid 70s—than similarly affected women who are most susceptible from their mid 60s to mid 70s, suggest the findings of a long term study. The most vulnerable regions of the brain are those involved in processing [...]
As we age, our cognitive and motor functions deteriorate, which in turn affects our independence and overall quality of life. Research efforts to ameliorate or even completely abolish this have given rise to technologies that show a lot of promise. Among these is non-invasive brain stimulation: a term encompassing a set of techniques that can [...]
Infants whose mothers regularly use language to describe what their child is thinking or feeling, have higher levels of the hormone oxytocin, finds a new study led by UCL researchers. Oxytocin, a hormone that is involved in a range of psychological processes, plays an important role in social relationships, such as the development of the [...]
Researchers have found that mindfulness showed promise in improving quality of life and advance care planning outcomes in patients and their family caregivers coping with advanced cancer. Both patients with poor cancer prognoses and family caregivers often use avoidant coping strategies, such as delaying advance care planning discussions. Mindfulness emphasizes paying attention to the present [...]
The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, according to a new study. The study establishes a mortality timer that reveals how long a cell has left before it dies, and may lead to new longevity treatments that could extend human lifespan. “Ageing is [...]
