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A new gene-editing treatment for prion disease has been developed that extends lifespan by around 50 per cent in a mouse model. The treatment, which uses base editing to make a single-letter change in DNA, reduced levels of the disease-causing prion protein in the brain by as much as 60 per cent, according to the [...]
People with COPD experience more falls and related injuries requiring medical care when using common fall-risk increasing drugs, according to a new study. Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disease, comprising several conditions, including chronic bronchitis and emphysema. Symptoms include breathlessness, fatigue and chronic cough. The disease is the fourth leading cause [...]
Myant Corp has acquired digital health company mmHg in an acquisition that aims to accelerate personalised, AI-enabled remote healthcare. mmHg is a digital health company specialising in remote blood pressure monitoring, cardiovascular risk reduction, and chronic disease management. Myant's has said the deal will expand its geographic footprint and market reach to the USA, where [...]
A groundbreaking study has identified a significant relationship between indoor temperatures and cognitive performance in older adults, shedding light on how climate change may pose an increased risk to cognitive health. The study found that older adults reported the least difficulty maintaining attention when their home temperatures were within 68 to 75˚F (20–24˚C). Outside of [...]
Mild cognitive impairment is linked to blood vessel dysfunction in the brain’s temporal lobes, the seat of memory, according to a new study. The findings, seen in people with and without signs of amyloid build up in the brain, suggest that microvascular trouble may be an important, early biomarker for dementia as well as a [...]
Among children with cancer, those with obesity at the time of diagnosis may face an elevated risk of dying, a recent population study has revealed. The retrospective study was based on information from the Cancer in Young People in Canada (CYP-C) database, including all children with newly diagnosed cancer aged 2 to 18 years across [...]
A new study has revealed how two proteins interact with water and other matrix components to regulate the mechanical behaviour of bone – findings that could open new doors to understanding bone biology and potentially lead to the development of innovative treatments for bone-related diseases like osteoporosis. The team has uncovered the essential roles of [...]
A large clinical food trial will test whether a combination of probiotics and prebiotics (BondiaÒ or SBD111) will help manage bone health in women aged 60 years and above. The first participants have joined the study and the Institute seeks additional women for the 18-month effort. Principal investigator Dr. Shivani Sahni, and her research team [...]
A new study backed by US$5.3m will examine the correlation between walking and mild cognitive impairment (MCI) in the hope of unveiling neural mechanisms underlying the relation between mobility and cognitive decline to enhance early Alzheimer's Disease and Related Dementias (ADRD) risk prediction. The study will begin by screening research participants for MCI, a condition [...]
Older people in the US are increasingly interested in using technology to age well and independently in their current homes and communities, A new report has revealed. The report found that 80 per cent of older Americans currently own at least one type of tech that enables ageing at home, and over half express a [...]
