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The first comprehensive cell atlas of ageing human muscle reveals the intricate genetic and cellular processes behind muscle deterioration and mechanisms to counteract it. How muscle changes with ageing, and tries to fight its effects, is now better understood at the cellular and molecular level with the first comprehensive atlas of ageing muscles in humans. [...]

The British Society for Research on Ageing (BSRA) is calling for more public backing in the UK for research to help people stay healthier for longer, as an alternative to charities that support research on diseases. The greatest risk factor for disease is ageing, but we have very little charitable support for research into how [...]

In the realm of aged bone repair, materiobiology emphasises the meticulous modulation and restoration of biological functions at various levels — cellular, tissue, organ, and organism — through the use of functionalized biomaterials. In the elderly, a multitude of factors contribute to diminished bone regeneration capabilities. These include a reduction in the self-renewal and differentiation [...]

A new study has found that accelerated ageing was more common in recent birth cohorts and was associated with increased incidence of early-onset solid tumours. Researchers from Washington University School of Medicine in St. Louis hypothesised that increased biological age, indicative of accelerated ageing, may contribute to the development of early-onset cancers. These cancers are [...]

Global life expectancy has increased by 6.2 years since 1990 according to a new study published in The Lancet, as the world addressed major killers including diarrhoea, lower respiratory infections, and stroke. Over the past three decades, reductions in death from leading killers fuelled this progress, including diarrhoea and lower respiratory infections, as well as [...]

Hevolution Foundation has announced its first life science impact investment of $20 million to help Aeovian Pharmaceuticals advance its innovative platform of selective mTORC1 inhibitors which could lead to several promising therapies for disease of ageing. The investment was the leading contribution in a $50 million Series A financing extension for Aeovian. Evolution Foundation has [...]

New research conducted in mice has provided insights into what’s going on at the molecular level that could cause people with diabetes to develop Alzheimer’s disease. Diabetes and Alzheimer’s are two of the fastest-growing health concerns worldwide. Diabetes alters the body’s ability to turn food into energy and affects an estimated 1 in 10 US [...]

A new analysis led by researchers at the University of Oxford and funded by the Nuffield Foundation has found that virtually all care homes forced to close in England by the Care Quality Commission are run on a for-profit basis. The results, published today in The Lancet Healthy Longevity, raise questions about the role of the private sector [...]

A new study has explored the role of tryptophan - an essential amino acid found in many protein-rich foods - in the development of arthritis. The study, carried out by the University of Colorado Department of Medicine, has identified the means in which bacteria in the digestive system can break down tryptophan in the diet [...]

A new probe aimed at gaining a better understanding of the ageing process to help shape treatments that could reverse degenerative processes has been launched. Researchers are focusing in on one of the hallmarks of ageing - the increased frequency of senescent cells in most organs, leading to tissue dysfunction. The presence of these cells [...]