News
New research links gut inflammation to Alzheimer's, with higher levels associated with more amyloid plaque in the brain. Animal studies have shown Alzheimer's can be passed to young mice through gut microbe transfer, strengthening the link between the gut and the brain. A 2023 study adds support to inflammation as a possible mechanism. Barbara Bendlin, [...]
New research has linked richer social ties to better cognitive health in older adults, offering new insight into how connection relates to thinking and memory. Earlier studies found links between specific social factors and health. This study appears to be the first to build combined social profiles and test how they relate to cognitive health [...]
A new AI tool flags early Alzheimer's, identifying about four in five people who would otherwise be missed by clinicians. Trained on UCLA Health patient records and tuned to work more fairly across Black, Latino and Asian patients who are often underdiagnosed, the system aims to find people earlier, when treatment and lifestyle changes can [...]
L-Nutra will establish an Abu Dhabi centre to produce medical and longevity nutrition for the Middle East and North Africa. The company has added US$36.5m to its Series D, taking the round to US$83.5m and supporting plans for a joint venture to make medical and longevity nutrition for the region. Founded in 2009 by longevity [...]
Gap is partnering with Spear Bio on Bio-Hermes-002, an Alzheimer's study comparing blood and digital biomarkers across cognitive conditions. The observational platform study compares blood-based and digital biomarkers (measurable signs in blood or behaviour) across a broad range of cognitive conditions, alongside MRI and PET brain scans and diverse racial and ethnic groups, to generate [...]
Scanning ultrasound was safe and well tolerated in a first-in-human Alzheimer’s pilot study contucted in Australia. The pilot split 12 people with Alzheimer’s into groups to test different levels of ultrasound stimulation in the brain. Alzheimer’s is the most common form of dementia and affects more than 480,000 Australians. Without major scientific advances, 6.4 million [...]
BioAge Labs is expanding its lead drug candidate into diabetic macular oedema, with plans to start a phase 1b/2a trial in mid-2026. The clinical-stage biotechnology company will test BGE-102, an oral therapy, in patients with the condition, which is one of the most common causes of vision impairment among people with diabetes. Diabetic macular oedema [...]
The USC Clinical Trial Recruitment Lab will fund four projects testing how AI can strengthen recruitment for Alzheimer's trials. The initiative, dedicated to accelerating and improving Alzheimer's clinical trials, selected the projects from more than 30 applicants to explore digital approaches. Alzheimer's clinical trials are more complex, costlier and take longer than those in other [...]
Insilico Medicine has agreed a US$66m deal with a Chinese biotech for half of the rights to a brain-penetrant Parkinson's drug. Under the agreement, the artificial intelligence-powered drug developer will take the lead on bringing the preclinical asset, dubbed ISM8969, into a phase 1 trial. Hygtia Therapeutics will then take over for further studies and [...]
Scientists have developed a nanoparticle strategy to broaden which disease-causing proteins medicines can target, giving options for dementia and brain cancer. A perspective outlines an approach designed to remove harmful proteins that drive disease. By broadening the proteins that can be treated, the technology could help tackle conditions such as dementia and brain cancer. The [...]
